Protein hierarchy, classification, folding, functional roles, Life Sciences, Biochemistry, Biomedical Science

Structure of Proteins

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11 Chapters

1 Hour

Structure of Proteins

Explore the fundamental principles underpinning the structure of proteins, from the building blocks of amino acids to the intricate folding and assembly that determines protein function. This course equips learners with a clear and thorough foundation in protein structure, classification, and their central biological roles.

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Free

Structure of Proteins

11 Chapters

1 Hour

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Structure of Proteins

About The Course

Learning Outcomes

Course Modules

1

About The Course

Structure of Proteins introduces the hierarchical organisation and diversity of protein molecules, essential for students of biology, chemistry, and medicine. The course explains each level of protein structure—primary, secondary, tertiary, and quaternary—using real biological examples. Learners will discover how the amino acid sequence dictates folding, stability, and ultimately, biological activity. Content also covers common protein classifications (such as fibrous, globular, and conjugated proteins), factors influencing protein shape and stability, and the effects of mutations and denaturation. The course closes with applications of protein structure knowledge in biotechnology, health, and disease.

2

Learning Outcomes

Describe the four levels of protein structure and their significance
Understand the chemical bonds and interactions stabilising protein conformations
Distinguish between main types and classes of proteins
Explain the impact of mutations, post-translational modifications, and denaturation
Apply concepts of protein structure to examples in health, disease, and biotechnology

3

Course Modules

Chapter 1 Introduction to Proteins and Amino Acids

Chapter 2 Primary Structure: Amino Acid Sequencing

Chapter 3 Secondary Structure: Helices, Sheets, and Motifs

Chapter 4 Tertiary Structure: Protein Folding and Stability

Chapter 5 Quaternary Structure and Protein Complexes

Chapter 6 Protein Classification and Examples

Chapter 7 Forces and Bonds in Protein Structure

Chapter 8 Protein Denaturation and Misfolding

Chapter 9 Post-Translational Modifications

Chapter 10 Proteins in Health, Disease, and Biotechnology

Chapter 11 Summary & Review

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